RU-58841 50mg/mL 30mL
Potent Topical Androgen Blocker for Hair Loss Research
RU-58841 is a non-steroidal antiandrogen applied topically to block DHT at the hair follicle receptor level, studied for androgenetic alopecia without the systemic side effect profile of oral 5-alpha reductase inhibitors.
Potent Topical Androgen Blocker for Hair Loss Research
RU-58841 (PSK-3841) competitively inhibits dihydrotestosterone binding to androgen receptors within the scalp follicle. Its topical formulation limits systemic absorption, making it a subject of significant interest for hairloss research as a localized alternative.
As one of the most studied compounds in the skin & anti-aging research space, RU-58841 has attracted sustained scientific interest across Androgenetic alopecia research, Hair follicle preservation studies, Topical anti-androgen protocols. Peer-reviewed evidence indicates that shown to promote hair regrowth in macaque models, which has positioned RU-58841 as a reference standard for researchers exploring androgenetic alopecia research outcomes. The compound's selectivity and documented tolerability in preclinical models have contributed to a rapidly growing body of literature over the past decade.
RU-58841 Documented Benefits: 3 Documented Mechanisms
Local DHT Blockade
Competes with DHT at the androgen receptor within the hair follicle, interrupting the miniaturization process.
Minimal Systemic Absorption
Topical application limits systemic androgen receptor inhibition, reducing risk of off-target effects.
Follicle Preservation
Research models show RU-58841 can slow or reverse follicle miniaturization associated with androgenetic alopecia.
How RU-58841 Works: Molecular Mechanism & Pathway
Competitive non-steroidal androgen receptor antagonist binding AR at the hair follicle, preventing DHT-induced follicle miniaturization.
The 3 primary research pathways identified for RU-58841 — Local DHT Blockade, Minimal Systemic Absorption, Follicle Preservation — collectively point to a compound with pleiotropic activity across interconnected biological systems. Studies have further shown that minimal plasma levels detected after topical application, reinforcing the mechanistic picture established in earlier cell-line work. Unlike single-pathway agents, RU-58841's broad receptor engagement profile continues to generate hypotheses for novel applications beyond its originally characterized use cases.
Research Protocols & Compound Combinations
RU-58841 is routinely studied alongside GHK-Cu and Melanotan II in skin & anti-aging-focused compound panels. Researchers investigating androgenetic alopecia research have found that pairing compounds with complementary receptor profiles can produce additive results while keeping individual doses within well-characterized ranges. Preliminary evidence that used widely in hair loss research community has informed several of these multi-compound protocol designs.
Purity, Testing & Research Grade Standards
All RU-58841 research material offered through this catalog is manufactured under controlled conditions and independently verified by a third-party laboratory prior to release. Each lot undergoes High-Performance Liquid Chromatography (HPLC) analysis to confirm ≥98% purity, with identity confirmed via mass spectrometry. The accompanying Certificate of Analysis (CoA) documents the exact purity, molecular weight confirmation, and lot-specific testing date — data that should accompany any reproducible research protocol. Lyophilized powder formulation ensures maximum stability during shipping and storage at −20°C long-term or 4°C for short-term use.
◈ Key Highlights
- Shown to promote hair regrowth in macaque models
- Minimal plasma levels detected after topical application
- Used widely in hair loss research community
Ideal For
- Androgenetic alopecia research
- Hair follicle preservation studies
- Topical anti-androgen protocols
Intended for laboratory use only. Not for human or animal consumption. Not FDA approved. Handle in appropriate lab settings only.
What the Research Shows
The following data points are derived from peer-reviewed preclinical and clinical studies on RU-58841. All studies cited in compound profiles are indexed in PubMed or published in peer-reviewed journals.
Shown to promote hair regrowth in macaque models
Minimal plasma levels detected after topical application
Used widely in hair loss research community
Third-Party Verified Every Batch
Each vial of RU-58841 is independently tested by a third-party laboratory before fulfillment. You receive the actual CoA (Certificate of Analysis) documentation with your order.
